In a review of rupatadine published in 2008, the primary focus was on its role as an antihistamine, with a thorough evaluation of its pharmacology and inter- action with histamine H1-receptors. At the time, however, evidence was already emerging of a broader mechanism...
Patients with chronic diseases, including chronic respiratory diseases, usually have considerably impaired sleep quality that may increase the frequency of exacerbations and severity of symptoms, lead to difficulty in patient management, and reduce quality of life...
Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H1-receptor antagonists have in the treatment of these disorders. However, histamine is clearly not the only...
Background: Allergic rhinitis and rhinosinusitis, common and debilitating conditions, should be managed in accordance with guideline recommendations. Guideline adherence shows regional di erences. As of now, there is little data from Asia and none from Malaysia on the...
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