Purpose: Patients with chronic spontaneous urticaria (CSU) have an increased risk for comorbid autoimmune diseases. In this retrospective multicenter study of CSU patients, we evaluated clinical and laboratory features of CSU associated with a higher risk of comorbid...
Background: IgG autoantibodies against the high-affinity IgE receptor, FcɛRIα, contribute the pathogenesis of autoimmune chronic spontaneous urticaria (CSU). However, it is not known whether such patients also exhibit IgM or IgA autoantibod- ies against FcɛRIα. To...
The identification of the causes of chronic spontaneous urticaria (CSU) is difficult. The recognition of functional autoantibodies against FcεRI and/or against IgE in some patients with CSU led to the concept of autoimmune etiology of the disease. Clinical and...
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