Introduction: Flare reactions arise due to the release of vasodilators from sensory nerves caused by antidromic transmission of action potentials after the induction of itch. Objective: We investigated the link between flare and itch using 3 models of itch. Methods:...
Background: Atopic dermatitis (AD) is a common skin disorder. Its diagnosis relieson clinical judgment. Mild and untypical manifestations may cause diagnostic difficulties. Biomarkers for the differential diagnostic workup of AD are needed. Objective: To test whether...
Background: In skin diseases and experimental models of pruritus, pure itch is accompanied by additional sensations that are poorly characterized. Objectives: This study compared the sensory qualities evoked by different models of experimentally induced pruritus...
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