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The expression of IL-17, in chronic spontaneous urticaria is linked to semaphorin5A

The expression of IL-17, in chronic spontaneous urticaria is linked to semaphorin5A

by admin | May 31, 2021

Background: Patients with chronic spontaneous urticaria (CSU), an autoimmune disorder, show increased skin expression of IL-17A and can benefit from treatment with the anti-IL-17A biologic secukinumab. The mechanisms that drive IL-17A expression in CSU are currently...
Interleukin-17 is a potential player and treatment target in severe chronic spontaneous urticaria

Interleukin-17 is a potential player and treatment target in severe chronic spontaneous urticaria

by admin | Oct 6, 2020

Background: Chronic spontaneous urticaria (CSU) is considered an autoimmune disorder in 50% of cases at least, in which T- and mast cell mediators are considered to be the primary cause of symptoms. However , H1-antihistamines, cyclosporine A, and omalizumab fail to...

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