The skin as an organ has many functions of which the protection against environmental threats may be the most important. Recent investigations have broadened our understanding of the cellular mechanisms of host defense responses of the skin. Interestingly, the three...
Most parasitic skin infections are averted by very efficient strategies of preventing pathogen invasion. Innate immune cells such as mast cells, macrophages and dendritic cells are responsible for detecting parasites and for recruiting proinflammatory cells that help...
Mast cells are not only potent effector cells in allergy, but are also important players in protective immune responses against pathogens. Most of our knowledge about mast cells in innate immunity is derived from models of sepsis, whereas their role in innate immune...
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