Background: Mastocytosis encompasses a spectrum of disorders in which different organs and tissues are affected by the clonal expansion of mast cells. The skin is one of the most frequently affected organs. The clinical manifestations of mastocytosis are linked to the...
Mastocytosis comprises a group of diseases characterized by an increase in the number of mast cells in one or more organs.It is divided into cutaneous and systemic forms (Table1). Cutaneous mastocytosis often occurs in early childhood andis usually characterized by...
Background: Mastocytosis is a heterogeneous disease characterized by a clonal expansion of mast cells in various organs. The vast majority of patients affected suffer from signs and symptoms caused by mediator release from mast cells. Although the disease burden is...
The European Competence Network on Mas- tocytosis (ECNM) was initiated in 2002 as a multidisci- plinary and multinational cooperative approach to in- crease awareness and to improve diagnosis and therapy of mastocytosis. The network is composed of local cen- ters,...
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