Skin microdialysis (SMD) is a versatile sampling technique that can be used to recover soluble endogenous and exog‐ enous molecules from the extracellular compartment of human skin. Due to its minimally invasive character, SMD can be applied in both clinical and...
Background: Platelet-activating factor (PAF) causes wheal and flare responses which are abrogated by H1-antihistamines giving rise to the hypothesis that PAF- induced wheal development is secondary to histamine release from dermal mast cells. But is this hypothesis...
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