Introduction: Chronic spontaneous urticaria(CSU) is a common and hard to treat condition associated with a substantial negative impact on patients’ quality of life(QoL). Clinical studies have shown that rupatadine is effective and safe in the treatment of CSU, but...
Background: Recommendations in current guidelines for the treatment of chronic spontaneous urticaria (CSU) in infants and children are mostly based on extrapolation of data obtained in adults. This study reports the efficacy and safety of rupatadine, amodern H1and PAF...
Chronic cold urticaria (ColdU) is a rare disease charac-terized by mast cell-mediated wheals and angioedema following cold exposure. Second-generation H1-anti-histamines, such as rupatadine, are the recommended first-line therapy. As of yet, the effects of rupatadine...
In a review of rupatadine published in 2008, the primary focus was on its role as an antihistamine, with a thorough evaluation of its pharmacology and inter- action with histamine H1-receptors. At the time, however, evidence was already emerging of a broader mechanism...
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