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Originalarbeiten, Bücher, Buchkapitel und Übersichtsartikel von Prof. Marcus Maurer
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A novel treatment option for mast cell-mediated diseases
Filename | 76. Maurer et al.,Miltefosine Review,JDT2013.pdf |
Filesize | 432,56 kB |
Version | r.076 |
Date added | Juni 26, 2020 |
Downloaded | 0 times |
Category | Reviews |
Tags | allergic diseases, mast cells, miltefosine, treatment |
Authors | Maurer, M., Magerl, M., Metz, M., Weller, K., and Siebenhaar, F. |
Citation | Maurer, M., Magerl, M., Metz, M., Weller, K., and Siebenhaar, F.: Miltefosine: A novel treatment option for mast cell-mediated diseases. J. Dermatol. Treat. 2013: 24; 244-249. |
DocNum | r.76 |
DocType | |
Edition; Page | 24; 244-249 |
IF | 1.76 |
Publisher | J. Dermatol. Treat. |
ReleaseDate | 2013 |
Mast cell-mediated diseases such as urticaria, mastocytosis and atopic dermatitis are common, disabling and hard to treat. Recently, the lipid raft modulator miltefosine has been shown to inhibit mast cell activation in vitro and in vivo. Moreover, three randomized and placebo-controlled trials have assessed the effects of miltefosine in mast cell-driven conditions. Here, we review the experimental and clinical evidence in support of miltefosine as a novel treatment option for mast cell- mediated diseases and we discuss the most imminent questions and issues that need to be addressed by future research and clinical trials.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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