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Originalarbeiten, Bücher, Buchkapitel und Übersichtsartikel von Prof. Marcus Maurer
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Clinical features and epidemiology of cutaneous leishmaniasis and Leishmania major/HIV co-infection in Cameroon: results of a large cross-sectional study
Filename | 128._Ngouateu_et_al_Cutaneous_Leishmaniasis_in_Cameroon_TRSTMH_2012.pdf |
Filesize | 626,33 kB |
Version | o.128 |
Date added | Juni 3, 2020 |
Downloaded | 0 times |
Category | Original Work |
Authors | Ngouateu, O. B., Kollo, P., Ravel, C., Derreure, J., Kamtchouing, P., Same-Ekobo, A., von Stebut, E., Maurer, M. and Dondji, B. |
Citation | Ngouateu, O. B., Kollo, P., Ravel, C., Derreure, J., Kamtchouing, P., Same-Ekobo, A., von Stebut, E., Maurer, M. and Dondji, B.: Clinical features and epidemiology of cutaneous leishmaniasis and Leishmania major/HIV co-infection in Cameroon: Results of a large cross-sectional study. T. Roy. Soc. Trop. Med. H. 2012: 106; 137-142. IF: 1.82 |
Corresponding authors | Dondji, B. |
DocNum | O.128 |
DocType | |
Edition; Page | 106; 137-142 |
IF | 1.82 |
Publisher | T. Roy. Soc. Trop. Med. H. |
ReleaseDate | 2012 |
Cutaneous leishmaniasis (CL) is endemic in Central Africa, including Cameroon. However, data on its prevalence and co-infection with HIV are scarce. Here we present the results of a large cross-sectional study reporting the prevalence, clinical features and species identification of CL and HIV co-infection in northern Cameroon. A total of 32 466 subjects were clinically screened for CL during a door-to-door survey, followed by parasitological diagnosis in the field laboratory. Amongst the subjects surveyed, 146 (0.4%) were diagnosed with active CL. Seven (4.8%) of these 146 CL patients tested positive for HIV-1 and/or HIV-2. The number of lesions per CL patient ranged from 1 to 20. Three of the five subjects with >10 active lesions were co-infected with HIV. In both CL and HIV co-infected subjects, three successful parasite isolates were identified as Leishmania major by PCR. This first report of L. major/HIV co-infection in Cameroon and Central Africa confirms the endemicity of CL in the region and highlights a worsened CL pathology in HIV co-infected individuals. These findings provide important data necessary for the development and implementation of successful control programmes against CL and HIV in this geographical area.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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