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Omalizumab in chronic urticaria

Filename 61. Metz Maurer, Omalizumab in CU. COACI 2012.pdf
Filesize 248,05 kB
Version r.061
Date added Juni 26, 2020
Downloaded 0 times
Category Reviews
Tags anti-immunoglobulin (Ig) E, mast cell, physical urticaria, spontaneous urticaria, Xolair
Authors Metz, M. and Maurer, M.
Citation Metz, M. and Maurer, M.: Omalizumab in chronic urticaria. Curr. Opin. Allergy Clin. Immunol. 2012: 12; 406-411.
Corresponding authors Maurer, M.
DocNum R.61
DocType PDF
Edition; Page 12; 406-411
IF 3.39
Publisher Curr. Opin. Allergy Clin. Immunol.
ReleaseDate 2012

Purpose of review: The current EAACI/GA2LEN/EDF/WAO treatment guidelines for the management of urticaria recommend omalizumab as fourth-line therapy. Within the last year, many reports of omalizumab treatment in chronic urticaria have been published.

Recent findings: Two multicenter, randomized, placebo-controlled trials in chronic spontaneous urticaria have shown excellent efficacy of omalizumab. Furthermore, in various case series and case reports, omalizumab has been shown to be effective also in inducible urticarias; however, no randomized placebo-controlled trial has been performed yet to thoroughly investigate the efficacy of omalizumab in inducible urticarias.

Summary: In this review, all published information on the use of omalizumab in urticaria will be summarized and discussed with special emphasis on reports published within the last year. The available data indicate that omalizumab is an effective and well tolerated drug in antihistamine-resistant chronic urticaria.

 

(Last update: 12.2023)

Number of original publications in peer-reviewed journals:580
Number of reviews in peer-reviewed journals:210
Number of publications (original work and reviews) in peer-reviewed journals:790
Cumulative IF for original publications in peer-reviewed journals:4196.39
Cumulative IF for reviews in peer-reviewed journals:1409.32
Cumulative IF of publications (original work & reviews) in peer-reviewed journals:5605.71
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023)36836

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