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Results and relevance of critical temperature threshold testing in patients with acquired cold urticaria

Filename 91. Mlynek et al., Results and relevance of critical temp,BJD 2010.pdf
Filesize 349,12 kB
Version o.091
Date added Mai 27, 2020
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Category Original Work
Authors Młynek, A., Magerl, M., Siebenhaar, F., Weller, K., Vieira dos Santos, R., Zuberbier, T., Zalewska-Janowska, A., and Maurer, M.
Citation Młynek, A., Magerl, M., Siebenhaar, F., Weller, K., Vieira dos Santos, R., Zuberbier, T., Zalewska-Janowska, A., and Maurer, M.: Results and relevance of critical temperature threshold testing in patients with acquired cold urticaria. Brit. J. Dermatol. 2010: 162; 198-200. IF: 4.35
Corresponding authors Maurer, M.
DocNum O.91
DocType PDF
Edition; Page 162; 198-200
IF 4.35
Publisher Brit. J. Dermatol.
ReleaseDate 2010

Background: Acquired cold urticaria (ACU) is a physical urticaria characterized by local skin reactions after cold exposure. Objective markers of disease severity and activity would be helpful. Unfortunately, such markers are not yet available, even though stimulation time and temperature thresholds are promising candidates.

Objectives: We assessed and correlated critical temperature thresholds (CTTs) with disease severity and activity in patients with ACU.

Methods: CTTs were determined in 45 patients with ACU by TempTest-based cold contact stimulation tests (Emo Systems GmbH, Berlin, Germany), and ACU severity and activity were assessed using Likert scales.

Results: Patients with ACU exhibited mean ± SEM CTTs of 17 ± 6 C (range 4– 27 C). These thresholds and their changes correlated with the severity (r = 0Æ53, P < 0Æ05) and activity of disease (r = 0Æ64, P < 0Æ05), respectively.

Conclusions: These findings indicate that temperature threshold measurements may be used for assessing disease severity and activity as well as the efficacy of therapeutic measures including novel treatment approaches for cold urticaria.

 

(Last update: 12.2023)

Number of original publications in peer-reviewed journals:580
Number of reviews in peer-reviewed journals:210
Number of publications (original work and reviews) in peer-reviewed journals:790
Cumulative IF for original publications in peer-reviewed journals:4196.39
Cumulative IF for reviews in peer-reviewed journals:1409.32
Cumulative IF of publications (original work & reviews) in peer-reviewed journals:5605.71
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023)36836

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