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Role and relevance of mast cells in fungal infections
Filename | 70. Saluja et al,Role and relevance of MC in fungal infections Frontiersin 2012.pdf |
Filesize | 358,22 kB |
Version | r.070 |
Date added | Juni 26, 2020 |
Downloaded | 0 times |
Category | Reviews |
Tags | C-type lectin-like receptors, fungal infection, mast cell, pro-inflammatory mediators, Toll-like receptors |
Authors | Saluja, R., Metz, M., and Maurer, M. |
Citation | Saluja, R., Metz, M., and Maurer, M.: Role and relevance of mast cells in fungal infections. Front. Immunol. 2012: 3; 1-11. |
Corresponding authors | Maurer, M. |
DocNum | r.70 |
DocType | |
Edition; Page | 3; 1-11 |
IF | N/A |
Publisher | Front. Immunol. |
ReleaseDate | 2012 |
In addition to their detrimental role in allergic diseases, mast cells (MCs) are well known to be important cells of the innate immune system. In the last decade, they have been shown to contribute significantly to optimal host defense against numerous pathogens including parasites, bacteria, and viruses. The contribution of MCs to the immune responses in fun- gal infections, however, is largely unknown. In this review, we first discuss key features of mast cell responses to pathogens in general and then summarize the current knowledge on the function of MCs in the defense against fungal pathogens. We especially focus on the potential and proven mechanisms by which MCs can detect fungal infections and on possible MC effector mechanisms in protecting from fungal infections.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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