Publications

Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD

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Angioedema Activity Score (AAS): A Valid and Reliable Tool to Use in Asian Patients

Filename 365. Kulthanan et al., Thai AAS, BiomedResInternJ 2019.pdf
Filesize 1 MB
Version o.365
Date added June 5, 2019
Downloaded 2 times
Category Original Work
Tags angioedema, Angioedema Activity Score
Authors Kulthanan, K., Chularojanamontri, L., Rujitharanawong, C., Weerasubpong, P., Weller, K., and Maurer, M.
Citation Kulthanan, K., Chularojanamontri, L., Rujitharanawong, C., Weerasubpong, P., Weller, K., and Maurer, M.: Angioedema activity score (AAS): a valid and reliable tool to use in Asian patients. Biomed. Res. Int. 2019: 9157895.
Corresponding authors Maurer, M.
DocNum o.365
DocType PDF
Edition; Page 9157895
IF 2.28
Publisher Biomed. Res. Int.
ReleaseDate 2019

The Angioedema Activity Score (AAS) is recommended by the EAACI/GA2 LEN/EDF/WAO guidelines for urticaria as the standard measure for assessing disease activity in patients with recurrent angioedema (RAE). To date, it has been translated into 80 languages for use in 52 countries, but it has not been formally validated in Asian patient populations. As RAE may be different in Asian and non-Asian patients, it is important to validate and characterize the reliability of tools to assess RAE disease activity in Asian patients. this study proposed to demonstrate the validity and reliability of the AAS in Asian patients. Accordingly, this study aimed to generate and validate the Thai version of the AAS and to characterize its reliability in Asian patients, specifically in Thailand. A structured translation was conducted with approval from the original authors. the Patient Global Assessment of Disease Activity (PGA-DA) was used as an instrument to compare with the Thai version of the AAS. In total, 86 patients with RAE participated in the study. Seventy-six (88%) patients had RAE with chronic spontaneous urticaria. the Thai AAS was found to be a valid and reliable instrument, with high convergent and known-groups validities, excellent internal consistency, and good testretest reliability. the validity and reliability of the AAS for assessing RAE disease activity in Asian patients have been demonstrated by our study, making it the first to do so. This will help promote the use of the AAS, in clinical trials and practice, in Asia. It will also facilitate the comparison of disease activity in patients with RAE inside and outside Asia in future studies. However, a limitation of this study was its small number of patients.

(Last update: 08.2021)

Number of publications (original work and reviews) in peer-reviewed journals: 636
Number of original publications in peer-reviewed journals: 462
Number of reviews in peer-reviewed journals: 174
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: 3834,12
Cumulative IF for original publications in peer-reviewed journals: 3043,14
Cumulative IF for reviews in peer-reviewed journals: 790,98
Citations, Hirsch index: (view on Web of Science) 26429