Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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Anti-Immunoglobulin E Treatment of Patients with Recalcitrant Physical Urticaria
Filename | 104. Metz et al Anti-IgE Treatment IAAI 2011.pdf |
Filesize | 206.73 KB |
Version | o.104 |
Date added | May 28, 2020 |
Downloaded | 3 times |
Category | Original Work |
Authors | Metz, M., Altrichter, S., Ardelean, E., Keßler, B., Krause, K., Magerl, M., Siebenhaar, F., Weller, K., Zuberbier, T., and Maurer, M. |
Citation | Metz, M., Altrichter, S., Ardelean, E., Keßler, B., Krause, K., Magerl, M., Siebenhaar, F., Weller, K., Zuberbier, T., and Maurer, M.: Anti-immunglobulin E treatment of patients with recalcitrant physical urticaria. Int. Arch. Allergy Immunol. 2011: 154; 177-180. IF: 2.40 |
Corresponding authors | Maurer, M. |
DocNum | O.104 |
DocType | |
Edition; Page | 154; 177-180 |
IF | 2.40 |
Publisher | Int. Arch. Allergy Immunol. |
ReleaseDate | 2011 |
In physical urticaria, exogenous physical factors such as thermal triggers, solar radiation and mechanic triggers including friction or pressure are responsible for the elicitation of symptoms in the skin of patients. Avoidance of the respective stimulus is usually difficult or impossible, and many patients are not sufficiently treated with standard antihistamines. We report that treatment with omalizumab (Xolair ) of 7 patients with physical urticarias [solar urticaria (n = 2), urticaria factitia/symptomatic dermographism (n = 2), cold urticaria, delayed pressure urticaria and localized heat urticaria] resulted in complete symptom control within days after the first injection in 5 patients. In 1 patient, symptoms improved after increasing the dose of omalizumab, and 1 patient with localized heat urticaria did not respond significantly to treatment. Before anti-immunoglobulin E treatment, all patients had suffered from their physical urticaria for years and had had numerous unsuccessful therapies. The overall excellent responses to omalizumab treatment reported here indicate that anti-immunoglobulin E is a safe and effective treatment for recalcitrant physical urticarias.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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