Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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Anti-pruritic effect of sertaconazole 2% cream in atopic dermatitis subjects: a prospective, randomized, double-blind, vehicle-controlled, multi-centre clinical trial of efficacy, safety and local tolerability
Filename | 248. Ständer et al., Sertaconazole 2 Proc.,ActDermVen2016.pdf |
Version | o.248 |
Date added | July 30, 2020 |
Downloaded | 0 times |
Category | Original Work |
Tags | atopic dermatitis, itch, Pruritus, sertaconazole |
Authors | Ständer, S., Metz, M., Ramos, M. H., Maurer, M. Schoepke, N., Tsianakas, A., Zeidler, C., and Luger, T. A. |
Citation | Ständer, S., Metz, M., Ramos, M. H., Maurer, M. Schoepke, N., Tsianakas, A., Zeidler, C., and Luger, T. A.: Anti-pruritic effect of sertaconazole 2% cream in atopic dermatitis subjects: a prospective, randomized, double-blind, vehicle-controlled, multi-centre clinical trial of efficacy, safety and local tolerability. Acta Derm. Venereol. 2016: 96; 792-796. |
Corresponding authors | Ständer, S. |
DocNum | O.248 |
DocType | |
Edition; Page | 96; 792-796 |
IF | 3.65 |
Publisher | Acta Derm. Venereol. |
ReleaseDate | 2016 |
This study was a prospective, parallel-group, randomi-zed, double-blind, vehicle-controlled, multi-centre clini-cal trial to compare the efficacy of topical sertaconazole 2% cream with vehicle in reducing chronic pruritus in subjects with atopic dermatitis, and to assess its safety and local tolerability. A total of 70 subjects applied either of the 2 treatments twice daily for a period of 4 weeks on affected, itchy skin areas. Treatment efficacy was eva-luated primarily considering the item itch intensity on a 5-point verbal rating scale. Insomnia, state of atopic dermatitis (Scoring Atopic Dermatitis; SCORAD), qua-lity of life and therapy benefit were also assessed. No significant difference between active treatment and ve-hicle was found at any of the time-points for any of the investigated parameters. Under the experimental conditions of the study, sertaconazole 2% cream did not exert anti-pruritic effects that were better than vehicle in subjects with atopic dermatitis who had chronic pruritus.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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