Publications

Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD

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Anti-pruritic effect of sertaconazole 2% cream in atopic dermatitis subjects: a prospective, randomized, double-blind, vehicle-controlled, multi-centre clinical trial of efficacy, safety and local tolerability

Filename 248. Ständer et al., Sertaconazole 2 Proc.,ActDermVen2016.pdf
Version o.248
Date added July 30, 2020
Downloaded 0 times
Category Original Work
Tags atopic dermatitis, itch, Pruritus, sertaconazole
Authors Ständer, S., Metz, M., Ramos, M. H., Maurer, M. Schoepke, N., Tsianakas, A., Zeidler, C., and Luger, T. A.
Citation Ständer, S., Metz, M., Ramos, M. H., Maurer, M. Schoepke, N., Tsianakas, A., Zeidler, C., and Luger, T. A.: Anti-pruritic effect of sertaconazole 2% cream in atopic dermatitis subjects: a prospective, randomized, double-blind, vehicle-controlled, multi-centre clinical trial of efficacy, safety and local tolerability. Acta Derm. Venereol. 2016: 96; 792-796.
Corresponding authors Ständer, S.
DocNum O.248
DocType PDF
Edition; Page 96; 792-796
IF 3.65
Publisher Acta Derm. Venereol.
ReleaseDate 2016

This study was a prospective, parallel-group, randomi-zed, double-blind, vehicle-controlled, multi-centre clini-cal trial to compare the efficacy of topical sertaconazole 2% cream with vehicle in reducing chronic pruritus in subjects with atopic dermatitis, and to assess its safety and local tolerability. A total of 70 subjects applied either of the 2 treatments twice daily for a period of 4 weeks on affected, itchy skin areas. Treatment efficacy was eva-luated primarily considering the item itch intensity on a 5-point verbal rating scale. Insomnia, state of atopic dermatitis (Scoring Atopic Dermatitis; SCORAD), qua-lity of life and therapy benefit were also assessed. No significant difference between active treatment and ve-hicle was found at any of the time-points for any of the investigated parameters. Under the experimental conditions of the study, sertaconazole 2% cream did not exert anti-pruritic effects that were better than vehicle in subjects with atopic dermatitis who had chronic pruritus.

 

(Last update: 12.2023)

Number of original publications in peer-reviewed journals:580
Number of reviews in peer-reviewed journals:210
Number of publications (original work and reviews) in peer-reviewed journals:790
Cumulative IF for original publications in peer-reviewed journals:4196.39
Cumulative IF for reviews in peer-reviewed journals:1409.32
Cumulative IF of publications (original work & reviews) in peer-reviewed journals:5605.71
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023)36836

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