Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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ASSURE-CSU: a real-world study of burden of disease in patients with symptomatic chronic spontaneous urticaria
Filename | 219. Weller et al.,ASSURE-CSU, CTA 2015.pdf |
Filesize | 798.54 KB |
Version | o.219 |
Date added | July 30, 2020 |
Downloaded | 0 times |
Category | Original Work |
Tags | Absenteeism, angioedema, Chronic idiopathic urticaria, chronic spontaneous urticaria, Disease burden, Economic cost, Humanisticburden, Observational, Presenteeism |
Authors | Weller, K., Maurer, M. Grattan, C., Nakonechna, A., Abuzakouk, M., Bérard, F., Sussman, G., Giménez-Arnau, A. M., Ortiz de Frutos, J., Knulst, A., Canonica, G. W., Hollis, K., McBride, D., and Balp, M. M. |
Citation | Weller, K., Maurer, M. Grattan, C., Nakonechna, A., Abuzakouk, M., Bérard, F., Sussman, G., Giménez-Arnau, A. M., Ortiz de Frutos, J., Knulst, A., Canonica, G. W., Hollis, K., McBride, D., and Balp, M. M.: ASSURE-CSU: a real-world study of burden of disease in patients with symptomatic chronic spontaneous urticaria. Clin. Transl. Allergy 2015: 5; 29. |
Corresponding authors | Weller, K. |
DocNum | O.219 |
DocType | |
Edition; Page | 5; 29 |
IF | N/A |
Publisher | Clin. Transl. Allergy |
ReleaseDate | 2015 |
Background: Chronic spontaneous urticaria (CSU) formerly known as chronic idiopathic urticaria (CIU) is a severe and distressing skin condition that remains uncontrolled in approximately one half of patients, despite the use of licensed, recommended doses of modern, second-generation H1-antihistamines. So far, the humanistic, societal and economic burden of CSU/CIU has not been well quantified. Therefore it is important to broaden our understanding of how CSU/CIU impacts patients, society, and healthcare systems, by determining the disease burden of CSU/CIU and the associated unmet need; as well as to further guide the use of new treatments in an efficient and cost-effective manner.
Methods: ASSURE-CSU is an observational, multi center study being conducted in the UK, Germany, Canada, France,Italy, Spain, and The Netherlands. The study comprises a retrospective medical chart review in conjunction with patient surveys (including validated tools for assessment of disease impact) and an 8-day patient diary. The primary objectives of the study are to describe patient demographics, medical history, treatments, and healthcare resource utilization based on medical-record data and to assess the impact of disease, healthcare resource utilization, work days missed,and productivity loss based on patient-reported data. Approximately 700 patients (aged≥18 years) will be enrolled who have CSU/CIU despite currently receiving treatment, and have had persistent symptoms for at least 12 months.Data will be collected retrospectively for the 12 months (±1 month) prior to enrollment wherever possible, and prospectively for the week following enrollment.
Discussion: ASSURE-CSU will be the first study to examine the economic and humanistic burden of disease in patients diagnosed with CSU/CIU who are symptomatic despite treatment. By combining retrospective evaluation of medical records with prospective patient surveys and 8-day diaries, across seven different countries, the ASSURE-CSU study will contribute to a better understanding and acknowledgement of the burden of disease in patients with symptomatic chronic spontaneous urticaria.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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