Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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Cold urticaria – what we know and what we do not know
Filename | 167. Maltseva et al., Cold urticaria what we know, Allergy 2021.pdf |
Filesize | 1.06 MB |
Version | r.167 |
Date added | March 15, 2021 |
Downloaded | 4 times |
Category | Reviews |
Tags | cold stimulation testing, Cold urticaria, cryoglobulinemic vasculitis, cryoglobulins, familial cold autoinflammatory syndrome |
Authors | Maltseva, N., Borzova, E., Fomina, D., Bizjak, M., Terhorst-Molawi, D., Košnik, M., Kulthanan, K., Meshkova, R., Thomsen, S. F., and Maurer, M. |
Citation | Maltseva, N., Borzova, E., Fomina, D., Bizjak, M., Terhorst-Molawi, D., Košnik, M., Kulthanan, K., Meshkova, R., Thomsen, S. F., and Maurer, M.: Cold urticaria – what we know and what we do not know. Allergy 2021 |
Corresponding authors | Maurer, M. |
DocNum | r.167 |
DocType | |
IF | 14.71 |
Publisher | Allergy |
ReleaseDate | 2021 |
Cold urticaria (ColdU) is a common form of chronic inducible urticaria characterized by the development of wheals, angioedema or both in response to cold exposure. Recent research and guideline updates have advanced our understanding and management of ColdU. Today, its pathophysiology is thought to involve the cold-induced
formation of autoallergens and IgE to these autoallergens, which provoke a release of proinflammatory mediators from skin mast cells. The classification of ColdU includes typical and atypical subtypes. We know that cold-induced wheals usually develop on rewarming and resolve within an hour and that anaphylaxis can occur. The diagnosis relies on the patient’s history and cold stimulation testing. Additional diagnostic workup, including a search for underlying infections, should only be done if indicated by the patient’s history. The management of ColdU includes cold avoidance, the regular use of nonsedating antihistamines and the off-label use of omalizumab. However, many questions regarding ColdU remain unanswered. Here, we review what is known about ColdU, and we present important unanswered questions on the epidemiology, underlying pathomechanisms, clinical heterogeneity and treatment outcomes. Our aim is to guide future efforts that will close these knowledge gaps and advance the
management of ColdU.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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