Publications

Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD

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Effect of dietary fiber and metabolites on mast cell activation and mast cell-associated diseases

Filename 137. Folkerts et al., Dietary fiber, FrontImmun2018.pdf
Filesize 926 KB
Version r.137
Date added June 17, 2020
Downloaded 1 time
Category Reviews
Tags Allergy, asthma, dietary fiber, mast cells, short-chain fatty acids
Authors Folkerts, J., Stadhouders, R., Redegeld, F. A., Tam, S. Y., Hendriks, R. W., Galli, S., and Maurer, M.
Citation Folkerts, J., Stadhouders, R., Redegeld, F. A., Tam, S. Y., Hendriks, R. W., Galli, S., and Maurer, M.: Effect of dietary fiber and metabolites on mast cell activation and mast cell-associated diseases. Front. Immunol. 2018: 9; 1067. eCollection.
Corresponding authors Maurer, M.
DocNum r.137
DocType PDF
Edition; Page 9; 1067. eCollection.
IF 4.72
Publisher Front. Immunol
ReleaseDate 2018

Many mast cell-associated diseases, including allergies and asthma, have seen a strong increase in prevalence during the past decades, especially in Western(ized) countries. It has been suggested that a Western diet may contribute to the prevalence and manifestation of allergies and asthma through reduced intake of dietary fiber and the subsequent production of their metabolites. Indeed, dietary fiber and its metabolites have been shown to positively influence the development of immune disorders via changes in microbiota composition and the regulation of B- and T-cell activation. However, the effects of these dietary components on the activation of mast cells, key effector cells of the inflammatory response in allergies and asthma, remain poorly characterized. Due to their location in the gut and vascularized tissues, mast cells are exposed to high con- centrations of dietary fiber and/or its metabolites. Here, we provide a focused overview of current findings regarding the direct effects of dietary fiber and its various metabolites on the regulation of mast cell activity and the pathophysiology of mast cell-associated diseases.

(Last update: 08.2021)

Number of publications (original work and reviews) in peer-reviewed journals: 636
Number of original publications in peer-reviewed journals: 462
Number of reviews in peer-reviewed journals: 174
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: 3834,12
Cumulative IF for original publications in peer-reviewed journals: 3043,14
Cumulative IF for reviews in peer-reviewed journals: 790,98
Citations, Hirsch index: (view on Web of Science) 26429