Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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Mast cells drivers of disease and therapeutic targets
| Filename | 132. Siebenhaar et al., MC drivers of disease,TREIMM2018.pdf |
| Filesize | 1.53 MB |
| Version | r.132 |
| Date added | June 17, 2020 |
| Downloaded | 2 times |
| Category | Reviews |
| Authors | Siebenhaar, F., Redegeld, F. A., Bischoff, S. C., Gibbs, B. F., and Maurer, M |
| Citation | Siebenhaar, F., Redegeld, F. A., Bischoff, S. C., Gibbs, B. F., and Maurer, M.: Mast cells drivers of disease and therapeutic targets. Trends Immunol. 2018: 39; 151-162. |
| Corresponding authors | Maurer, M |
| DocNum | r.132 |
| DocType | |
| Edition; Page | 39; 151-162 |
| IF | 13.00 |
| Publisher | Trends Immunol. |
| ReleaseDate | 2018 |
Mast cells (MCs) contribute to the pathogenesis of a multitude of diseases that include MC-driven disorders such as urticaria, type I allergies, and mastocytosis as well as autoimmune and other inflammatory disorders and malignant tumors. Here, we review and discuss the results of studies that identified and character- ized how MCs contribute to disease and, importantly, what strategies may be used to target MCs and MC effects therapeutically. Specifically, we discuss the most common approaches for investigating the role and relevance of MCs in various diseases. We also review current therapeutic approaches aimed at modulating MC numbers, inhibiting MCs and/or preventing MC activation, mod- ulating MC signal transduction and protection from the effects of MC mediators.
(Last update: 12.2023)
| Number of original publications in peer-reviewed journals: | 580 |
| Number of reviews in peer-reviewed journals: | 210 |
| Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
| Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
| Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
| Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
| Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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