Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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Microbiota-dependent and –independent effects of dietary fiber on human health
Filename | 155. Cai et al., Microbiota dietary fiber, BJP 2020.pdf |
Filesize | 2.15 MB |
Version | r.155 |
Date added | June 17, 2020 |
Downloaded | 2 times |
Category | Reviews |
Authors | Cai, Y., Folkerts, J., Folkerts, G., Maurer, M., and Braber, S. |
Citation | Cai, Y., Folkerts, J., Folkerts, G., Maurer, M., and Braber, S.: Microbiota-dependent and –independent effects of dietary fiber on human health. Brit. J. Pharmacol. 2020: 177; 1363-1381. |
Corresponding authors | Braber, S. |
DocNum | r.155 |
DocType | |
Edition; Page | 177; 1363-1381 |
IF | 8.74 |
Publisher | Brit. J. Pharmacol |
ReleaseDate | 2020 |
Dietary fibre, such as indigestible oligosaccharides and polysaccharides, occurs in many foods and has gained considerable importance related to its beneficial effects on host health and specific diseases. Dietary fibre is neither digested nor absorbed in the small intestine and modulates the composition of the gut microbiota. New evidence indicates that dietary fibre also interacts directly with the epithelium and immune cells throughout the gastrointestinal tract by microbiota‐independent effects. This review focuses on how dietary fibre improves human health and the reported health benefits that are connected to molecular pathways, in (a) a microbiota‐independent manner, via interaction with specific surface receptors on epithelial and immune cells regulating intestinal barrier and immune function, and (b) a microbiota‐dependent manner via maintaining intestinal homeostasis by promoting beneficial microbes, including Bifidobacteria and Lactobacilli, limiting the growth, adhesion, and cytotoxicity of pathogenic microbes, as well as stimulating fibre‐derived microbial short‐chain fatty acid production.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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