Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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New topics in bradykinin research
| Filename | 56. Maurer et al. New topics in bradykinin, Allergy 2011.pdf |
| Filesize | 446.28 KB |
| Version | r.056 |
| Date added | June 26, 2020 |
| Downloaded | 0 times |
| Category | Reviews |
| Tags | angioedema, bradykinin, C1-esterase inhibitor, Icatibant |
| Authors | Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb-Lundberg, F., Lötvall, J., and Magerl, M. |
| Citation | Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb-Lundberg, F., Lötvall, J., and Magerl, M.: New topics in bradykinin research. Allergy 2011: 66; 1397-1406. |
| Corresponding authors | Maurer, M. |
| DocNum | R.56 |
| DocType | |
| Edition; Page | 66; 1397-1406 |
| IF | 6.27 |
| Publisher | Allergy |
| ReleaseDate | 2011 |
Bradykinin has been implicated to contribute to allergic inflammation and the pathogenesis of allergic conditions. It binds to endothelial B1 and B2 receptors and exerts potent pharmacological and physiological effects, notably, decreased blood
pressure, increased vascular permeability and the promotion of classical symptoms of inflammation such as vasodilation, hyperthermia, oedema and pain. Towards potential clinical benefit, bradykinin has also been shown to exert potent antithrombogenic, antiproliferative and antifibrogenic effects. The development of pharmacologically active substances, such as bradykinin receptor blockers, opens up new therapeutic options that require further research into bradykinin. This review presents current understanding surrounding the role of bradykinin in nonallergic angioedema and other conditions seen by allergists and emergency physicians, and its potential role as a therapeutic target.
(Last update: 12.2023)
| Number of original publications in peer-reviewed journals: | 580 |
| Number of reviews in peer-reviewed journals: | 210 |
| Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
| Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
| Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
| Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
| Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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