Publications

Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD

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New topics in bradykinin research

Filename 56. Maurer et al. New topics in bradykinin, Allergy 2011.pdf
Filesize 446 KB
Version r.056
Date added June 26, 2020
Downloaded 0 times
Category Reviews
Tags angioedema, bradykinin, C1-esterase inhibitor, Icatibant
Authors Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb-Lundberg, F., Lötvall, J., and Magerl, M.
Citation Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb-Lundberg, F., Lötvall, J., and Magerl, M.: New topics in bradykinin research. Allergy 2011: 66; 1397-1406.
Corresponding authors Maurer, M.
DocNum R.56
DocType PDF
Edition; Page 66; 1397-1406
IF 6.27
Publisher Allergy
ReleaseDate 2011

Bradykinin has been implicated to contribute to allergic inflammation and the pathogenesis of allergic conditions. It binds to endothelial B1 and B2 receptors and exerts potent pharmacological and physiological effects, notably, decreased blood
pressure, increased vascular permeability and the promotion of classical symptoms of inflammation such as vasodilation, hyperthermia, oedema and pain. Towards potential clinical benefit, bradykinin has also been shown to exert potent antithrombogenic, antiproliferative and antifibrogenic effects. The development of pharmacologically active substances, such as bradykinin receptor blockers, opens up new therapeutic options that require further research into bradykinin. This review presents current understanding surrounding the role of bradykinin in nonallergic angioedema and other conditions seen by allergists and emergency physicians, and its potential role as a therapeutic target.

(Last update: 08.2021)

Number of publications (original work and reviews) in peer-reviewed journals: 636
Number of original publications in peer-reviewed journals: 462
Number of reviews in peer-reviewed journals: 174
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: 3834,12
Cumulative IF for original publications in peer-reviewed journals: 3043,14
Cumulative IF for reviews in peer-reviewed journals: 790,98
Citations, Hirsch index: (view on Web of Science) 26429