Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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Subcutaneous self-injections of C1 inhibitor: an effective and safe treatment in a patient with hereditary angioedema
Filename | 238. Weller et al., Subcut. self-inj. C1Inh HAE, CED 2016.pdf |
Filesize | 79.28 KB |
Version | o.238 |
Date added | July 30, 2020 |
Downloaded | 4 times |
Category | Original Work |
Authors | Weller, K., Krüger, R., Maurer, M. and Magerl, M. |
Citation | Weller, K., Krüger, R., Maurer, M. and Magerl, M.: Subcutaneous self-injections of C1 inhibitor: an effective and safe treatment in a patient with hereditary angioedema. Clin. Exp. Dermatol. 2016: 41; 91-93. |
Corresponding authors | Maurer, M. |
DocNum | O.238 |
DocType | |
Edition; Page | 41; 91-93 |
IF | 1.58 |
Publisher | Clin. Exp. Dermatol. |
ReleaseDate | 2016 |
A 25-year-old woman presented to our clinic with a history of recurrent swelling and abdominal symptoms for > 20 years. The patient’s father was similarly affected. Thepatient was diagnosed with hereditary angiooedema (HAE) due to C1 inhibitor deficiency. This was initially managed with systemic androgens, but the symptoms of hyperandrogenism eventually became intolerable. Treatment with icatibant (anantagonist of bradykinin B2 receptors) was partially successful. We changed the therapy to prophylactic treatment with C1 inhibitor. Although the patient became completely symptom-free under this regimen, she found the repeated intravenous injections unacceptable. Therefore, we changed the route of administration to subcutaneous injections of C1 inhibitor 1000 U in 10 mL twice weekly, using a subcutaneous infusion kit. Since that time (December 2013), she has remained completely free ofsymptoms under this regimen. To our knowledge, this is the first report documentingthe efficacy and safety of subcutaneous injections of C1 inhibitor in a patient with HAE
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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