Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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The German version of the chronic urticaria quality-of-life questionnaire: factor analysis, validation, and initial clinical findings
Filename | 76. Mlynek et al, German Cu-QoL, Allergy 2009.pdf |
Filesize | 345.09 KB |
Version | o.076 |
Date added | May 27, 2020 |
Downloaded | 2 times |
Category | Original Work |
Authors | Młynek, A., Magerl, M., Hanna, M., Lhachimi, S., Baiardini, I., Canonica, G. W., Brzoza, Z., Kasperska-Zajac, A., Rogala, B., Zalewska-Janowska, A., Zuberbier, T., and Maurer, M. |
Citation | Młynek, A., Magerl, M., Hanna, M., Lhachimi, S., Baiardini, I., Canonica, G. W., Brzoza, Z., Kasperska-Zajac, A., Rogala, B., Zalewska-Janowska, A., Zuberbier, T., and Maurer, M.: The German version of the chronic urticaria quality-of-life questionnaire (CU-Q2oL): Factor analysis, validation and initial clinical findings. Allergy 2009: 64; 927-936. |
Corresponding authors | Maurer, M. |
DocNum | o.076 |
DocType | |
Edition; Page | 64; 927-936 |
IF | 6.38 |
Publisher | Allergy |
ReleaseDate | 2009 |
Background: Chronic urticaria (CU) is a common skin disorder that causes a substantial burden on patients quality-of-life (QoL). The aim of this work was to generate and validate a German version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) and to provide reference assessments of QoL.
Methods: The Italian CU-Q2oL was translated into German and administered to 157 CU patients. They also completed two well-established general dermatology QoL questionnaires, the Dermatology Life Quality Index (DLQI) and Skindex29. Factor analysis was used to identify scales of the German CU-Q2oL. Correlation to the DLQI and Skindex-29 was used for validation. Multiple linear regression was used to determine which patient characteristics were associated with which dimensions of QoL.
Results: The factor analysis identified six scales of the German CU-Q2oL: functioning, sleep, itching/embarrassment, mental status, swelling/eating, and limits looks, which accounted for 70% of the data variance. Five of these six scales showed good internal consistency, and another five demonstrated convergent validity. On a percentile scale, they had these median CU-Q2oL scores: 29 functioning, 44 sleep, 50 itching/embarrassment, 50 mental status, 31 swelling/eating, 31 limits looks. Disease severity significantly predicted scores on all scales. Age predicted functioning, sleep, itching/embarrassment, and swelling/ eating. Sex predicted itching/embarrassment and limits looks.
Conclusion: This study yielded a robust validation of the German version of the CU-Q2oL. It confirmed previous studies that CU has a clinically meaningful burden on QoL, especially for sleep and mental health, and that women are more severely affected by pruritus. The German CU-Q2oL should be widely adopted in clinical research on the treatment of CU.
(Last update: 12.2023)
Number of original publications in peer-reviewed journals: | 580 |
Number of reviews in peer-reviewed journals: | 210 |
Number of publications (original work and reviews) in peer-reviewed journals: | 790 |
Cumulative IF for original publications in peer-reviewed journals: | 4196.39 |
Cumulative IF for reviews in peer-reviewed journals: | 1409.32 |
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 5605.71 |
Total number of citations: 36,836, h-index: 99 (Web of Science December 2023) | 36836 |
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