Publications

Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD

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The icatibant outcome survey: treatment of laryngeal angioedema attacks

Filename 234. Longhurst et al., Icatibant Outcome S.,EJEM 2016.pdf
Filesize 80 KB
Version o.234
Date added July 30, 2020
Downloaded 0 times
Category Original Work
Tags acquired angioedema, C1 inhibitor deficiency, Hereditary Angioedema, Icatibant, laryngeal edema, observational study, therapy
Authors Longhurst, H. J., Aberer, W., Bouillet, L., Caballero, T., Maurer, M. Fabien, V., Zanichelli, A.
Citation Longhurst, H. J., Aberer, W., Bouillet, L., Caballero, T., Maurer, M. Fabien, V., Zanichelli, A.: The icatibant outcome survey: treatment of laryngeal angioedema attacks. Eur. J. Emerg. Med. 2016: 23; 224-227.
Corresponding authors Longhurst, H. J.
DocNum O.234
DocType PDF
Edition; Page 23; 224-227
IF 2.02
Publisher Eur. J. Emerg. Med.
ReleaseDate 2016

Objective: To characterize the management and outcomes of life-threatening laryngeal attacks of hereditary angioedema (HAE) treated with icatibant in the observational Icatibant Outcome Survey (NCT01034969) registry.

Methods: This retrospective analysis was based on data from patients with HAE type I/II who received health care professional-administered or self-administered icatibant to treat laryngeal attacks between September 2008 and May2013.

Results: Twenty centers in seven countries contributed data. Overall, 42 patients with HAE experienced 67icatibant-treated laryngeal attacks. Icatibant was self-administered for 62.3% of attacks (healthcare professional-administered, 37.7%). One icatibant injection was used for87.9% of attacks, with rescue or concomitant medicationused for 9.0%. The median time to treatment was 2.0 h(n=31 attacks) and the median time to resolution was 6.0 h(n=35 attacks).

Conclusions: This analysis describes successful use of icatibant for the treatment of laryngeal HAE attacks in a real-world setting.European Journal of Emergency Medicine00:000–000 Copyright © 2015 Wolters Kluwer Health, Inc.All rights reserved.

(Last update: 08.2021)

Number of publications (original work and reviews) in peer-reviewed journals: 636
Number of original publications in peer-reviewed journals: 462
Number of reviews in peer-reviewed journals: 174
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: 3834,12
Cumulative IF for original publications in peer-reviewed journals: 3043,14
Cumulative IF for reviews in peer-reviewed journals: 790,98
Citations, Hirsch index: (view on Web of Science) 26429