Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
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The icatibant outcome survey: treatment of laryngeal angioedema attacks
|Filename||234. Longhurst et al., Icatibant Outcome S.,EJEM 2016.pdf|
|Date added||July 30, 2020|
|Tags||acquired angioedema, C1 inhibitor deficiency, Hereditary Angioedema, Icatibant, laryngeal edema, observational study, therapy|
|Authors||Longhurst, H. J., Aberer, W., Bouillet, L., Caballero, T., Maurer, M. Fabien, V., Zanichelli, A.|
|Citation||Longhurst, H. J., Aberer, W., Bouillet, L., Caballero, T., Maurer, M. Fabien, V., Zanichelli, A.: The icatibant outcome survey: treatment of laryngeal angioedema attacks. Eur. J. Emerg. Med. 2016: 23; 224-227.|
|Corresponding authors||Longhurst, H. J.|
|Edition; Page||23; 224-227|
|Publisher||Eur. J. Emerg. Med.|
Objective: To characterize the management and outcomes of life-threatening laryngeal attacks of hereditary angioedema (HAE) treated with icatibant in the observational Icatibant Outcome Survey (NCT01034969) registry.
Methods: This retrospective analysis was based on data from patients with HAE type I/II who received health care professional-administered or self-administered icatibant to treat laryngeal attacks between September 2008 and May2013.
Results: Twenty centers in seven countries contributed data. Overall, 42 patients with HAE experienced 67icatibant-treated laryngeal attacks. Icatibant was self-administered for 62.3% of attacks (healthcare professional-administered, 37.7%). One icatibant injection was used for87.9% of attacks, with rescue or concomitant medicationused for 9.0%. The median time to treatment was 2.0 h(n=31 attacks) and the median time to resolution was 6.0 h(n=35 attacks).
Conclusions: This analysis describes successful use of icatibant for the treatment of laryngeal HAE attacks in a real-world setting.European Journal of Emergency Medicine00:000–000 Copyright © 2015 Wolters Kluwer Health, Inc.All rights reserved.
(Last update: 08.2021)
|Number of publications (original work and reviews) in peer-reviewed journals:||636|
|Number of original publications in peer-reviewed journals:||462|
|Number of reviews in peer-reviewed journals:||174|
|Cumulative IF of publications (original work & reviews) in peer-reviewed journals:||3834,12|
|Cumulative IF for original publications in peer-reviewed journals:||3043,14|
|Cumulative IF for reviews in peer-reviewed journals:||790,98|
|Citations, Hirsch index: (view on Web of Science)||26429|