Publications

Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD

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Unmet clinical needs in chronic spontaneous urticaria. A GA²LEN task force report

Filename 52. Maurer et al,Unmet needs 2011 Allergy.pdf
Version r.052
Date added June 26, 2020
Downloaded 3 times
Category Reviews
Tags antihistamines, epidemiology, impact, natural course, urticaria
Authors Maurer, M., Weller, K., Bindslev-Jensen, C., Giménez-Arnau, A., Bousquet, P., Bousquet, J., Canonica, G. W., Church, M. K., Godse, K. V., Grattan, C. E. J., Greaves, M. W., Hide, M., Kalogeromitros, D., Kaplan, A. P., Saini, S. S., Zhu, X. J., and Zuberbier, T.
Citation Maurer, M., Weller, K., Bindslev-Jensen, C., Giménez-Arnau, A., Bousquet, P., Bousquet, J., Canonica, G. W., Church, M. K., Godse, K. V., Grattan, C. E. J., Greaves, M. W., Hide, M., Kalogeromitros, D., Kaplan, A. P., Saini, S. S., Zhu, X. J., and Zuberbier, T.: Unmet clinical needs in chronic spontaneous urticaria. A GA2LEN task force report. Allergy 2011: 66; 317-330.
Corresponding authors Maurer, M.
DocNum r.052
DocType PDF
Edition; Page 66; 317-330
IF 6.27
Publisher Allergy
ReleaseDate 2011

Chronic spontaneous urticaria, formerly also known as chronic idiopathic urticaria and chronic urticaria (CU), is more common than previously thought. At any time, 0.5–1% of the population suffers from the disease (point prevalence). Although all age groups can be affected, the peak incidence is seen between 20 and 40 years of age. The duration of the disease is generally 1–5 years but is likely to be longer in more severe cases, cases with concurrent angioedema, in combination with physical urticaria or with a positive autologous serum skin test (autoreactivity). Chronic spontaneous urticaria has major detrimental effects on quality of life, with sleep deprivation and psychiatric comorbidity being frequent. It also has a large impact on society in terms of direct and indirect health care costs as well as reduced performance at work and in private life. In the majority of patients, an underlying cause cannot be identified making a causal and/or curative treatment difficult. Nonsedating H1-antihistamines are the mainstay of symptomatic therapy, but treatment with licensed doses relieves symptoms effectively in <50% of patients. Although guideline-recommended updosing up to fourfold increases symptom control in many patients, a substantial number of patients have only little benefit from H1-antihistamines. Consequently, there is a great need for new therapeutic strategies.

(Last update: 08.2021)

Number of publications (original work and reviews) in peer-reviewed journals: 636
Number of original publications in peer-reviewed journals: 462
Number of reviews in peer-reviewed journals: 174
Cumulative IF of publications (original work & reviews) in peer-reviewed journals: 3834,12
Cumulative IF for original publications in peer-reviewed journals: 3043,14
Cumulative IF for reviews in peer-reviewed journals: 790,98
Citations, Hirsch index: (view on Web of Science) 26429